Reaction Diagram
Physiology
Universal ID's | Text Annotations |
---|---|
|
|
Reaction |
Name
Structure
|
Kinetics | Depiction |
---|---|---|---|
X_CMX_CM+X_CM |
r2
CM
|
GeneralKinetics | X_CMX_CM+X_CM |
|
|
reaction rate (J): (0.04 + (0.4 * N_CM) + (2.0 * X_CM * X_CM / (1.0 + (X_CM * X_CM))) - (0.4 * X_CM * Y_CM) + (0.008 * X_CM * S_CM))[molecules.um-2.s-1]
inward current density (I): 0.0[pA.um-2] net charge valence (netValence): 0.0[1] |
|
Y_CMY_CM+Y_CM |
r3
CM
|
GeneralKinetics | Y_CMY_CM+Y_CM |
|
|
reaction rate (J): ((0.4 * X_CM) - (0.028 * Y_CM))[molecules.um-2.s-1]
inward current density (I): 0.0[pA.um-2] net charge valence (netValence): 0.0[1] |
|
L_sourceL_EC |
rx
EC
|
GeneralKinetics | L_sourceL_EC |
|
|
reaction rate (J): ((kf * L_source) - (kr * L_EC))[uM.s-1]
user defined (kr): 1.0[s-1] user defined (kf): 10.0[s-1] |
|
L_EC+R_CMS_CM |
r1
CM
|
GeneralKinetics | L_EC+R_CMS_CM |
|
|
reaction rate (J): ((kf * L_EC * R_CM) - (kr * S_CM))[molecules.um-2.s-1]
inward current density (I): 0.0[pA.um-2] net charge valence (netValence): 0.0[1] user defined (kr): 1.0[s-1] user defined (kf): 2.0[s-1.uM-1] |
Name |
Type
Electrical (Membrane Polarity)
|
---|---|
IC |
Compartment
(+) (-)
|
|
|
EC |
Compartment
(+) (-)
|
|
|
CM |
Membrane
N/A
|
|
|
Name | Structure | BioNetGen Definition |
---|---|---|
L_EC | EC | |
|
|
|
L_source | EC | |
|
|
|
N_CM | CM | |
|
|
|
Y_CM | CM | |
|
|
|
X_CM | CM | |
|
|
|
S_CM | CM | |
|
|
|
R_CM | CM | |
|
|
Name | Text Annotations | BioNetGen Definition |
---|
Name |
Type
Count
|
BioNetGen Definition |
---|
Applications
Name | Math Type | Annotation |
---|---|---|
Needle | Deterministic (ODE) Spatial (3D) |
Application - Needle
Species | Initial Condition | Diffusion Constant | ||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
L_EC | 0.0 [uM] | 15.0
[um2/s] L_source |
(((( - 5.0 + x) * ( - 5.0 + x)) + (( - 5.0 + y) * ( - 5.0 + y)) + (( - 2.5 + z) * ( - 2.5 + z))) < 1.0)
[uM]
|
10.0
[um2/s] | N_CM |
(0.2 * ((t >= 15.0) && (t <= 16.0)))
[uM]
|
0.1
[um2/s] | Y_CM |
2.0
[uM]
|
0.0
[um2/s] | X_CM |
0.14
[uM]
|
0.0
[um2/s] | S_CM |
0.0
[uM]
|
0.0
[um2/s] | R_CM |
100.0
[uM]
|
0.0
[um2/s]
|
|
Name | Reaction Mapping |
---|---|
r2 | included |
r3 | included |
rx | included |
r1 | included |
Name | End Time | Output Options |
---|---|---|
Simulation0 | 100.0 [s] |
OutputTimeStep 1.0 |
Dimension | Type | Subdomain | Adjacent Subvolumes | Size | Mapped Compartment |
---|---|---|---|---|---|
Volume | Analytical | IC | 11.821125 [um3] | IC | |
Volume | Analytical | EC | 113.17887499999999 [um3] | EC | |
Surface | EC_IC_membrane | EC | IC | 25.03574790171551 [um2] | CM |
Global Parameters
Name | Expression |
---|