ModelBricks - Model Print Page

Universal ID's	Text Annotations

Reactions See in Dashboard
Reaction	Name Structure	Kinetics	Depiction
cAMP_Unnamed_compartment+PKA_B_C_Unnamed_compartmentPKA_A_B_C_Unnamed_compartment	r7 Unnamed compartment	MassAction	cAMP_Unnamed_compartment+PKA_B_C_Unnamed_compartmentPKA_A_B_C_Unnamed_compartment
		reaction rate (J): (((Kf * cAMP_Unnamed_compartment) * PKA_B_C_Unnamed_compartment) - (Kr * PKA_A_B_C_Unnamed_compartment))[uM.s-1] forward rate constant (Kf): F_A_binding[s-1.uM-1] reverse rate constant (Kr): (F3 * A_kd * F_A_binding)[s-1]
PKA_B_Unnamed_compartment+C_Unnamed_compartmentPKA_B_C_Unnamed_compartment	r2 Unnamed compartment	MassAction	PKA_B_Unnamed_compartment+C_Unnamed_compartmentPKA_B_C_Unnamed_compartment
		reaction rate (J): (((Kf * PKA_B_Unnamed_compartment) * C_Unnamed_compartment) - (Kr * PKA_B_C_Unnamed_compartment))[uM.s-1] forward rate constant (Kf): (2.0 * C_kr2)[s-1.uM-1] reverse rate constant (Kr): (F1 * C_kr2 * C_kd)[s-1]
C_Unnamed_compartment+PKA_B_C_Unnamed_compartmentPKA_B_C2_Unnamed_compartment	r1 Unnamed compartment	MassAction	C_Unnamed_compartment+PKA_B_C_Unnamed_compartmentPKA_B_C2_Unnamed_compartment
		reaction rate (J): (((Kf * C_Unnamed_compartment) * PKA_B_C_Unnamed_compartment) - (Kr * PKA_B_C2_Unnamed_compartment))[uM.s-1] forward rate constant (Kf): C_kr2[s-1.uM-1] reverse rate constant (Kr): (2.0 * C_kd2 * C_kr2 * F2)[s-1]
cAMP_Unnamed_compartment+PKA_A_B_Unnamed_compartmentPKA_AA_BB_Unnamed_compartment	reaction8 Unnamed compartment	MassAction	cAMP_Unnamed_compartment+PKA_A_B_Unnamed_compartmentPKA_AA_BB_Unnamed_compartment
		reaction rate (J): (((Kf * cAMP_Unnamed_compartment) * PKA_A_B_Unnamed_compartment) - (Kr * PKA_AA_BB_Unnamed_compartment))[uM.s-1] forward rate constant (Kf): F_A_binding[s-1.uM-1] reverse rate constant (Kr): (2.0 * A2_kd * F_A_binding)[s-1]
PKA_A_B_C_Unnamed_compartment+C_Unnamed_compartmentPKA_B_A_C2	r5 Unnamed compartment	MassAction	PKA_A_B_C_Unnamed_compartment+C_Unnamed_compartmentPKA_B_A_C2
		reaction rate (J): (((Kf * PKA_A_B_C_Unnamed_compartment) * C_Unnamed_compartment) - (Kr * PKA_B_A_C2))[uM.s-1] forward rate constant (Kf): C_kr3[s-1.uM-1] reverse rate constant (Kr): (F4 * C_kd2 * C_kr3 * F2)[s-1]
PKA_B_C2_Unnamed_compartment+cAMP_Unnamed_compartmentPKA_B_A_C2	r6 Unnamed compartment	MassAction	PKA_B_C2_Unnamed_compartment+cAMP_Unnamed_compartmentPKA_B_A_C2
		reaction rate (J): (((Kf * PKA_B_C2_Unnamed_compartment) * cAMP_Unnamed_compartment) - (Kr * PKA_B_A_C2))[uM.s-1] forward rate constant (Kf): (2.0 * F_A_binding)[s-1.uM-1] reverse rate constant (Kr): (F3 * F4 * A_kd * F_A_binding)[s-1]
PKA_AA_BB_Unnamed_compartment+C_Unnamed_compartmentPKA_AA_BB_C	r0 Unnamed compartment	MassAction	PKA_AA_BB_Unnamed_compartment+C_Unnamed_compartmentPKA_AA_BB_C
		reaction rate (J): (((Kf * PKA_AA_BB_Unnamed_compartment) * C_Unnamed_compartment) - (Kr * PKA_AA_BB_C))[uM.s-1] forward rate constant (Kf): (2.0 * C_kr5)[s-1.uM-1] reverse rate constant (Kr): (F7 * C_kd * C_kr5 * F1 * F3)[s-1]
cAMP_Unnamed_compartment+PKA_A_B_C_Unnamed_compartmentPKA_AA_BB_C	r4 Unnamed compartment	MassAction	cAMP_Unnamed_compartment+PKA_A_B_C_Unnamed_compartmentPKA_AA_BB_C
		reaction rate (J): (((Kf * cAMP_Unnamed_compartment) * PKA_A_B_C_Unnamed_compartment) - (Kr * PKA_AA_BB_C))[uM.s-1] forward rate constant (Kf): F_A_binding[s-1.uM-1] reverse rate constant (Kr): (F7 * A2_kd * F_A_binding)[s-1]
PKA_B_Unnamed_compartment+cAMP_Unnamed_compartmentPKA_A_B_Unnamed_compartment	reaction7 Unnamed compartment	MassAction	PKA_B_Unnamed_compartment+cAMP_Unnamed_compartmentPKA_A_B_Unnamed_compartment
		reaction rate (J): (((Kf * PKA_B_Unnamed_compartment) * cAMP_Unnamed_compartment) - (Kr * PKA_A_B_Unnamed_compartment))[uM.s-1] forward rate constant (Kf): (2.0 * F_A_binding)[s-1.uM-1] reverse rate constant (Kr): (A_kd * F_A_binding)[s-1]
C_Unnamed_compartment+PKA_A_B_Unnamed_compartmentPKA_A_B_C_Unnamed_compartment	reaction4 Unnamed compartment	MassAction	C_Unnamed_compartment+PKA_A_B_Unnamed_compartmentPKA_A_B_C_Unnamed_compartment
		reaction rate (J): (((Kf * C_Unnamed_compartment) * PKA_A_B_Unnamed_compartment) - (Kr * PKA_A_B_C_Unnamed_compartment))[uM.s-1] forward rate constant (Kf): C_kr3[s-1.uM-1] reverse rate constant (Kr): (F3 * C_kd * C_kr3 * F1)[s-1]

Structures See in Dashboard
Name	Type Electrical (Membrane Polarity)
Unnamed compartment	Compartment (+) (-)

Species See in Dashboard
Name	Structure	BioNetGen Definition
PKA_B_Unnamed_compartment	Unnamed compartment

PKA_B_C_Unnamed_compartment	Unnamed compartment

C_Unnamed_compartment	Unnamed compartment

PKA_A_B_C_Unnamed_compartment	Unnamed compartment

PKA_B_C2_Unnamed_compartment	Unnamed compartment

PKA_A_B_Unnamed_compartment	Unnamed compartment

PKA_AA_BB_C	Unnamed compartment

PKA_B_A_C2	Unnamed compartment

PKA_AA_BB_Unnamed_compartment	Unnamed compartment

cAMP_Unnamed_compartment	Unnamed compartment

Molecules See in Dashboard
Name	Text Annotations	BioNetGen Definition

Observables See in Dashboard
Name	Type Count	BioNetGen Definition

Applications See in Dashboard
Name	Math Type	Annotation
test	Deterministic (ODE) Compartmental

Specifications(Species) - test See in Dashboard
Species	Initial Condition	Diffusion Constant
PKA_B_Unnamed_compartment	0.0125 [uM]	0.0 [um2/s]
PKA_B_C_Unnamed_compartment	0.0 [uM]	0.0 [um2/s]
C_Unnamed_compartment	5.025 [uM]	0.0 [um2/s]
PKA_A_B_C_Unnamed_compartment	0.0 [uM]	0.0 [um2/s]
PKA_B_C2_Unnamed_compartment	0.0 [uM]	0.0 [um2/s]
PKA_A_B_Unnamed_compartment	0.0 [uM]	0.0 [um2/s]
PKA_AA_BB_C	0.0 [uM]	0.0 [um2/s]
PKA_B_A_C2	0.0 [uM]	0.0 [um2/s]
PKA_AA_BB_Unnamed_compartment	0.0 [uM]	0.0 [um2/s]
cAMP_Unnamed_compartment	1000.0 [uM]	0.0 [um2/s]

Specifications(Reaction) - test See in Dashboard
Name	Reaction Mapping
r7	included
r2	included
r1	included
reaction8	included
r5	included
r6	included
r0	included
r4	included
reaction7	included
reaction4	included

Simulations - test See in Dashboard
Name	End Time	Output Options
Simulation0	1200.0 [s]	KeepEvery 20 KeepAtMost 6000
Copy of Simulation0	500000.0 [s]	KeepEvery 20 KeepAtMost 6000
Copy of Copy of Simulation0	500000.0 [s]	KeepEvery 20 KeepAtMost 6000
More points free R	500000.0 [s]	KeepEvery 20 KeepAtMost 6000
More points Holo	500000.0 [s]	KeepEvery 20 KeepAtMost 6000

Geometry non-spatial1833399091 See in Dashboard
(Origin: 0.0, 0.0, 0.0; Extent: 10.0, 10.0, 10.0[um])
Dimension	Type	Subdomain	Adjacent Subvolumes	Size	Mapped Compartment
	Compartmental	Compartment			Unnamed compartment

Global Parameters See in Dashboard
Name	Expression
F_B_binding	0.0031[uM-1.s-1]

B_kd	0.0029900000000000005[tbd]

B_factor	5.0[tbd]

F_A_binding	0.2[uM-1.s-1]

A_kd	0.001048[tbd]

A_factor	23.0[tbd]

C_kr	0.0023[s-1]

C_kd	2.518E-7[uM]

Vm	0.31[s-1]

Kf_A	0.08[1]

Kr_A	0.012[s-1]

Kf_B	0.082[1]

Kr_B	2.21E-4[s-1]

B1_factor	1.0[tbd]

F1	1.0[tbd]

F2	2310.0[tbd]

F3	13.5[tbd]

F4	206.0[tbd]

C_kd2	1.4E-6[tbd]

F5	275.0[tbd]

C_kr1	1.0[uM-1.s-1]

C_kr2	1.0[uM-1.s-1]

C_kr3	1.0[uM-1.s-1]

C_kr4	300.0[uM-1.s-1]

C_kr5	1.0[uM-1.s-1]

F6	1377.71[tbd]

F7	1380.0[tbd]

A2_kd	0.0057[uM]

Name - Boras_PKA_Dual_mutant_B-inhibited

BioModel ID - 91162818

Reaction Diagram

Physiology

Applications

Application - test

Global Parameters