ModelBricks - Model Print Page

Universal ID's	Text Annotations

Reactions See in Dashboard
Reaction	Name Structure	Kinetics	Depiction
C_Unnamed_compartment+PKA_B_Unnamed_compartmentPKA_B_C_Unnamed_compartment	reaction4 Unnamed compartment	MassAction	C_Unnamed_compartment+PKA_B_Unnamed_compartmentPKA_B_C_Unnamed_compartment
		reaction rate (J): (((Kf * C_Unnamed_compartment) * PKA_B_Unnamed_compartment) - (Kr * PKA_B_C_Unnamed_compartment))[uM.s-1] forward rate constant (Kf): (C_kr / C_kd)[s-1.uM-1] reverse rate constant (Kr): (C_kr * F1 * F3)[s-1]
cAMP_Unnamed_compartment+PKA_C_Unnamed_compartmentPKA_C_BB_Unnamed_compartment	reaction6 Unnamed compartment	MassAction	cAMP_Unnamed_compartment+PKA_C_Unnamed_compartmentPKA_C_BB_Unnamed_compartment
		reaction rate (J): (((Kf * cAMP_Unnamed_compartment) * PKA_C_Unnamed_compartment) - (Kr * PKA_C_BB_Unnamed_compartment))[uM.s-1] forward rate constant (Kf): F_B_binding[s-1.uM-1] reverse rate constant (Kr): (F1 * B_kd * F_B_binding)[s-1]
cAMP_Unnamed_compartment+PKA_C_BB_Unnamed_compartmentPKA_B_C_Unnamed_compartment	reaction18 Unnamed compartment	MassAction	cAMP_Unnamed_compartment+PKA_C_BB_Unnamed_compartmentPKA_B_C_Unnamed_compartment
		reaction rate (J): (((Kf * cAMP_Unnamed_compartment) * PKA_C_BB_Unnamed_compartment) - (Kr * PKA_B_C_Unnamed_compartment))[uM.s-1] forward rate constant (Kf): F_A_binding[s-1.uM-1] reverse rate constant (Kr): (F3 * A_kd * F_A_binding)[s-1]
PKA_Unnamed_compartment+cAMP_Unnamed_compartmentPKA_BBB_Unnamed_compartment	reaction21 Unnamed compartment	MassAction	PKA_Unnamed_compartment+cAMP_Unnamed_compartmentPKA_BBB_Unnamed_compartment
		reaction rate (J): (((Kf * PKA_Unnamed_compartment) * cAMP_Unnamed_compartment) - (Kr * PKA_BBB_Unnamed_compartment))[uM.s-1] forward rate constant (Kf): F_B_binding[s-1.uM-1] reverse rate constant (Kr): (B_kd * F_B_binding)[s-1]
PKA_BBB_Unnamed_compartment+cAMP_Unnamed_compartmentPKA_B_Unnamed_compartment	reaction7 Unnamed compartment	MassAction	PKA_BBB_Unnamed_compartment+cAMP_Unnamed_compartmentPKA_B_Unnamed_compartment
		reaction rate (J): (((Kf * PKA_BBB_Unnamed_compartment) * cAMP_Unnamed_compartment) - (Kr * PKA_B_Unnamed_compartment))[uM.s-1] forward rate constant (Kf): F_A_binding[s-1.uM-1] reverse rate constant (Kr): (A_kd * F_A_binding)[s-1]
PKA_BBB_Unnamed_compartment+C_Unnamed_compartmentPKA_C_BB_Unnamed_compartment	r0 Unnamed compartment	MassAction	PKA_BBB_Unnamed_compartment+C_Unnamed_compartmentPKA_C_BB_Unnamed_compartment
		reaction rate (J): (((Kf * PKA_BBB_Unnamed_compartment) * C_Unnamed_compartment) - (Kr * PKA_C_BB_Unnamed_compartment))[uM.s-1] forward rate constant (Kf): (C_kr / C_kd)[s-1.uM-1] reverse rate constant (Kr): (C_kr * F1)[s-1]
C_Unnamed_compartment+PKA_Unnamed_compartmentPKA_C_Unnamed_compartment	reaction5 Unnamed compartment	MassAction	C_Unnamed_compartment+PKA_Unnamed_compartmentPKA_C_Unnamed_compartment
		reaction rate (J): (((Kf * C_Unnamed_compartment) * PKA_Unnamed_compartment) - (Kr * PKA_C_Unnamed_compartment))[uM.s-1] forward rate constant (Kf): (C_kr / C_kd)[s-1.uM-1] reverse rate constant (Kr): C_kr[s-1]

Structures See in Dashboard
Name	Type Electrical (Membrane Polarity)
Unnamed compartment	Compartment (+) (-)

Species See in Dashboard
Name	Structure	BioNetGen Definition
cAMP_Unnamed_compartment	Unnamed compartment

PKA_B_Unnamed_compartment	Unnamed compartment

PKA_Unnamed_compartment	Unnamed compartment

PKA_C_BB_Unnamed_compartment	Unnamed compartment

PKA_BBB_Unnamed_compartment	Unnamed compartment

C_Unnamed_compartment	Unnamed compartment

PKA_C_Unnamed_compartment	Unnamed compartment

PKA_B_C_Unnamed_compartment	Unnamed compartment

Molecules See in Dashboard
Name	Text Annotations	BioNetGen Definition

Observables See in Dashboard
Name	Type Count	BioNetGen Definition

Applications See in Dashboard
Name	Math Type	Annotation
test	Deterministic (ODE) Compartmental

Specifications(Species) - test See in Dashboard
Species	Initial Condition	Diffusion Constant
cAMP_Unnamed_compartment	200.0 [uM]	0.0 [um2/s]
PKA_B_Unnamed_compartment	0.0 [uM]	0.0 [um2/s]
PKA_Unnamed_compartment	0.003 [uM]	0.0 [um2/s]
PKA_C_BB_Unnamed_compartment	0.0 [uM]	0.0 [um2/s]
PKA_BBB_Unnamed_compartment	0.0 [uM]	0.0 [um2/s]
C_Unnamed_compartment	2.5E-4 [uM]	0.0 [um2/s]
PKA_C_Unnamed_compartment	0.0 [uM]	0.0 [um2/s]
PKA_B_C_Unnamed_compartment	0.0 [uM]	0.0 [um2/s]

Specifications(Reaction) - test See in Dashboard
Name	Reaction Mapping
reaction4	included
reaction6	included
reaction18	included
reaction21	included
reaction7	included
r0	included
reaction5	included

Simulations - test See in Dashboard
Name	End Time	Output Options
Simulation0	1200.0 [s]	KeepEvery 20 KeepAtMost 6000
Copy of Simulation0	5000.0 [s]	KeepEvery 20 KeepAtMost 6000
C_kr=.23	1200.0 [s]	KeepEvery 20 KeepAtMost 6000
C_kr=23	1200.0 [s]	KeepEvery 20 KeepAtMost 6000
C_kd=.0038	1200.0 [s]	KeepEvery 20 KeepAtMost 6000
C_kd=.000038	1200.0 [s]	KeepEvery 20 KeepAtMost 6000
Kf_A=.8	1200.0 [s]	KeepEvery 20 KeepAtMost 6000
Kf_A=.008	1200.0 [s]	KeepEvery 20 KeepAtMost 6000
Kr_A=.12	1200.0 [s]	KeepEvery 20 KeepAtMost 6000
Kr_A=.0012	1200.0 [s]	KeepEvery 20 KeepAtMost 6000
Kf_B=.82	1200.0 [s]	KeepEvery 20 KeepAtMost 6000
Kf_B=.0082	1200.0 [s]	KeepEvery 20 KeepAtMost 6000
Kr_B=.00221	1200.0 [s]	KeepEvery 20 KeepAtMost 6000
Kr_B=.0000221	1200.0 [s]	KeepEvery 20 KeepAtMost 6000
Copy of Kr_B=.0000221	1200.0 [s]	KeepEvery 20 KeepAtMost 6000
F_B_binding=31.75	1200.0 [s]	KeepEvery 20 KeepAtMost 6000
F_B_binding=.3175	1200.0 [s]	KeepEvery 20 KeepAtMost 6000
B_factor=50	1200.0 [s]	KeepEvery 20 KeepAtMost 6000
B_factor=.5	1200.0 [s]	KeepEvery 20 KeepAtMost 6000
B_kd=.13	1200.0 [s]	KeepEvery 20 KeepAtMost 6000
B_kd=.0013	1200.0 [s]	KeepEvery 20 KeepAtMost 6000
A_kd=.3	1200.0 [s]	KeepEvery 20 KeepAtMost 6000
A_kd=.003	1200.0 [s]	KeepEvery 20 KeepAtMost 6000
F_A_binding=3	1200.0 [s]	KeepEvery 20 KeepAtMost 6000
F_A_binding=.03	2000.0 [s]	KeepEvery 20 KeepAtMost 6000
A_Factor=230	2000.0 [s]	KeepEvery 20 KeepAtMost 6000
A_Factor=2.3	2000.0 [s]	KeepEvery 20 KeepAtMost 6000

Geometry non-spatial1833399091 See in Dashboard
(Origin: 0.0, 0.0, 0.0; Extent: 10.0, 10.0, 10.0[um])
Dimension	Type	Subdomain	Adjacent Subvolumes	Size	Mapped Compartment
	Compartmental	Compartment			Unnamed compartment

Global Parameters See in Dashboard
Name	Expression
F_B_binding	3.175[uM-1.s-1]

B_kd	4.16E-4[tbd]

B_factor	5.0[tbd]

F_A_binding	0.3[uM-1.s-1]

A_kd	0.00452[tbd]

A_factor	23.0[tbd]

C_kr	2.3[s-1]

C_kd	4.4E-7[uM]

Vm	0.31[s-1]

Kf_A	0.08[1]

Kr_A	0.012[s-1]

Kf_B	0.082[1]

Kr_B	2.21E-4[s-1]

Factor	50000.0[1]

FreeR_factor	0.0[uM-1.s-1]

F1	3220.0[1]

F2	0.0[tbd]

F3	910.0[tbd]

Name - Boras_PKA-Dimer

BioModel ID - 91133993

Reaction Diagram

Physiology

Applications

Application - test

Global Parameters