Dashboard

Name - SpermCalcium

BioModel ID - 211839191

Reaction Diagram

reactionDiagram

Physiology

Universal ID's Text Annotations

Applications

Applications See in Dashboard
Name Math Type Annotation
Application0 Deterministic (ODE) Spatial (3D)

Application - Application0

Specifications(Species) - Application0 See in Dashboard
Species Initial Condition Diffusion Constant
CaRNE1 1000.0 [uM] 20.0 [um2/s]
CaRetic ((3000.0 * 18.0 / 602.0 / RNE) * 1.0) [uM] 20.0 [um2/s]
CaReticCal 0.0 [uM] 20.0 [um2/s]
CaRet_Slow ((3000.0 * 18.0 / 602.0 / RNE) * 18.0) [uM] 20.0 [um2/s]
CaRetSlow_Calcium 0.0 [uM] 20.0 [um2/s]
CaIn 0.1 [uM] Diffusion [um2/s]
IP3 0.0 [uM] 8.0 [um2/s]
Ip3buf 0.0 [uM] 0.0 [um2/s]
CaPr ((1000.0 * 2.0) * 18.0 / 602.0 / Cytosole) [uM] Diffusion [um2/s]
CaBuf 0.0 [uM] Diffusion [um2/s]
caMSlow ((1000.0 * 2.0) * 18.0 / 602.0 / Cytosole) [uM] Diffusion [um2/s]
CaMSlowCa 0.0 [uM] Diffusion [um2/s]
Specifications(Reaction) - Application0 See in Dashboard
Name Reaction Mapping
leakRNE included
SPCA included
CatSper included
PLCd included
IP3K included
LeakPP included
CalMod included
CaRetFast included
CaRetSlow included
PMCA included
CaM_slow included
IP3R included
Simulations - Application0 See in Dashboard
Name End Time Output Options
Calcium diffusionvariationosc 1000.0 [s]

OutputTimeStep 1.0

Geometry Geometry1120118915 See in Dashboard
(Origin: -12.5, 3.0, 3.9; Extent: 50.0, 3.5, 2.5[um])
Dimension Type Subdomain Adjacent Subvolumes Size Mapped Compartment
Volume Analytical subdomain2 0.12512500000000001 [um3] RNE
Volume Analytical subdomain1 18.032437500000004 [um3] Cytosole
Volume Analytical subdomain0 419.3424375000001 [um3] outside
Surface subdomain0_subdomain1_membrane subdomain0 | subdomain1 96.30630517752202 [um2] m0
Surface subdomain1_subdomain2_membrane subdomain1 | subdomain2 1.033529612708134 [um2] RNEmem

Global Parameters

Global Parameters See in Dashboard
Name Expression
kcatABHD 3.0[tbd]
Vabhd 0.0[tbd]
KmABHD 66.0[tbd]
CatSper_0 0.0[tbd]
CatSper0 0.0[tbd]
IC50AG 0.35[tbd]
K_abhdProgf 0.0[tbd]
K_abhdProgb 0.0[tbd]
K_CatSperf 0.0[tbd]
Popen 0.0[tbd]
K2 30.0[tbd]
K3 0.005[tbd]
K5 0.25[tbd]
Z (1.0 + (CaIn * K3 / (K1 * K2)) + (CaIn / K5) + ((CaIn ^ 2.0) * K3 / (K5 * K1 * K2)) + (IP3 / K1) + (IP3 * CaIn / (K1 * K2)) + (IP3 * CaIn / (K1 * K5)) + (IP3 * CaIn * CaIn / (K1 * K2 * K5)))[tbd]
w11 (IP3 * CaIn * 1.0 / (K1 * K5 * Z))[tbd]
K1 0.13[tbd]
DOLYA (CaIn / (CaIn + 0.7))[tbd]
NIP3R 1850.0[tbd]
Kserca 0.27[tbd]
Vserca 0.92[tbd]
kleakrne 0.1[tbd]
g0 0.0[tbd]
leakparam ((x < 28.0) * (t < 700.0))[tbd]
Vcatsperfake 0.7[tbd]
Diffusion 4.0[tbd]
Kd_CaRetic_slow 1.0[uM]
Vspca 0.93[tbd]
p_k 1.8[1]