Dashboard

Name - Rab5_switch

BioModel ID - 188458250

Reaction Diagram

reactionDiagram

Physiology

Universal ID's Text Annotations
Reactions See in Dashboard
Reaction
Name
Structure
Kinetics

Universal ID's:

Text Annotations:

lumped reaction rate (LumpedJ): (endosome * K1)[mole.s-1]
user defined (K1): 1.0[mol.s-1.l-1]

Universal ID's:

Text Annotations:

lumped reaction rate (LumpedJ): (endosome * ((Rab5_GDP * ((ke * t) / (100.0 + t))) / (1.0 + exp(((kg - Rab5_GTP) * kf)))))[mole.s-1]
user defined (ke): 0.3[s-1]
user defined (kf): 2.5[M-1]
user defined (kg): 0.1[M]

Universal ID's:

Text Annotations:

lumped reaction rate (LumpedJ): (endosome * (kminus1 * Rab5_GDP))[mole.s-1]
user defined (kminus1): 1.0[s-1]

Universal ID's:

Text Annotations:

lumped reaction rate (LumpedJ): (endosome * ((ke * Rab5_GTP) / (1.0 + exp(((kg - Rab7_GTP) * kf)))))[mole.s-1]
user defined (ke): 0.31[s-1]
user defined (kf): 3.0[M-1]
user defined (kg): 0.3[M]

Universal ID's:

Text Annotations:

lumped reaction rate (LumpedJ): (endosome * (kh * Rab5_GTP))[mole.s-1]
user defined (kh): 0.06[s-1]
Structures See in Dashboard
Name
Type
Electrical (Membrane Polarity)

Universal ID's:

Text Annotations:


Applications

Applications See in Dashboard
Name Math Type Annotation
Deterministic Deterministic (ODE) Compartmental

0 - Deterministic

Specifications(Species) - Deterministic See in Dashboard
Species Initial Condition Diffusion Constant
Rab5_GDP 1.0 0.0 [m2/s]
Rab5_GTP 0.001 0.0 [m2/s]
Rab7_GTP 0.001 0.0 [m2/s]
Specifications(Reaction) - Deterministic See in Dashboard
Name Reaction Mapping
Recruitment of Rab5_GDP included
Activation of Rab5 included
extraction of Rab5_GDP included
Hydrolysis of Rab5_GTP included
Hydrolysis of Rab5_GTP_d included
Simulations - Deterministic See in Dashboard
Name End Time Output Options
Simulation0 1000.0 [s]

KeepEvery 1

KeepAtMost 1000


Global Parameters

Global Parameters See in Dashboard
Name Expression