Dashboard

Name - Macrophage Cargo Capacity

BioModel ID - 158495696

Reaction Diagram

reactionDiagram

Physiology

Universal ID's Text Annotations

Applications

Applications See in Dashboard
Name Math Type Annotation
Matching w/ Matlab data Deterministic (ODE) Compartmental cloned from 'Matching w/ Matlab data' owned by user jsbaik Monobasic molecule M transport simulator v.1 Mt is total concentration of M in each compartment. a = apical lumen of intestine, where drug initially is introduced as high concentration. pH = 6.8 aMem = apical side membrane of enterocyte. Membrane potential Eam. -9.3mV c = cytosolic compartment of enterocyte. pH = 7.0 m = mitochondria of enterocyte. pH = 8.0 mMem = mitochondrial membrane Membrane potential Emm = -160mV b = basolateral lumen of enterocyte. pH = 7.4 bMem = basolateral side membrane of enterocyte. Membrane potential Ebm = 119mV

Application - Matching w/ Matlab data

Specifications(Species) - Matching w/ Matlab data See in Dashboard
Species Initial Condition Diffusion Constant
Mt_l 0.0 [uM] 0.0 [um2/s]
Mt_m 0.0 [uM] 0.0 [um2/s]
Mt_e 4.75 [uM] 0.0 [um2/s]
Mt_c 0.0 [uM] 0.0 [um2/s]
Specifications(Reaction) - Matching w/ Matlab data See in Dashboard
Name Reaction Mapping
flux_ac included
flux_cl included
flux_cm included
Simulations - Matching w/ Matlab data See in Dashboard
Name End Time Output Options
Clofazimine 30.0 [s]

KeepEvery 1

KeepAtMost 1000
Amiodarone 30.0 [s]

KeepEvery 1

KeepAtMost 1000
Bupivacaine 30.0 [s]

KeepEvery 1

KeepAtMost 1000
Chlorprothixene 300.0 [s]

KeepEvery 1

KeepAtMost 1000
Lidocaine 30.0 [s]

KeepEvery 1

KeepAtMost 1000
Celiprolol 300.0 [s]

KeepEvery 1

KeepAtMost 1000
Geometry non-spatial1067581628 See in Dashboard
(Origin: 0.0, 0.0, 0.0; Extent: 10.0, 10.0, 10.0[um])
Dimension Type Subdomain Adjacent Subvolumes Size Mapped Compartment
Compartmental Compartment mMem

Global Parameters

Global Parameters See in Dashboard
Name Expression