Physiology

Reaction Diagram

reactionDiagram

Cross-References

Annotations

Reactions

Reactions
Name
Structure
Kinetics
RhoGDP GDI GDI_RhoGDP RhoGDP_GDI_binding default GeneralKinetics
RhoGTP GDI GDI_RhoGTP RhoGTP_GDI_binding default GeneralKinetics

Reaction Name: RhoGDP_GDI_binding

Universal ID's

Text Annotations

Reaction Name: RhoGTP_GDI_binding

Universal ID's

Text Annotations

Reaction Name: RhoGDP_GDI_binding

Expressions

reaction rate

((k4 * RhoGDP * GDI) - (k5 * GDI_RhoGDP)) [umol.l-1.min-1]

Reaction Name: RhoGTP_GDI_binding

Expressions

reaction rate

((k6 * RhoGTP * GDI) - (k7 * GDI_RhoGTP)) [umol.l-1.min-1]

Structures

Name
Type
Electrical
default Compartment (+)   (-)

Structure Name: default

Universal ID's

Text Annotations

Species

Name
Structure
RhoGDP default
RhoGTP default
GDI default
GDI_RhoGDP default
GDI_RhoGTP default

Species Name: RhoGDP

Universal ID's

Text Annotations

Species Name: RhoGTP

Universal ID's

Text Annotations

Species Name: GDI

Universal ID's

Text Annotations

Species Name: GDI_RhoGDP

Universal ID's

Text Annotations

Species Name: GDI_RhoGTP

Universal ID's

Text Annotations

Molecules

Name
Description
G_protein G_protein ( State ~GTP ~GDP GDI Effector )
GDI GDI ( Rho )

Molucule Name: G_protein

Universal ID's

Text Annotations

Molucule Name: GDI

Universal ID's

Text Annotations

Observables

Name
Domain
Molecular Type
Sequence Type
O0_G_protein_tot Molecules G_protein Multimolecular
O0_GDI_tot Molecules GDI Multimolecular

Observables Name: O0_G_protein_tot

Universal ID's

Text Annotations

Observables Name: O0_GDI_tot

Universal ID's

Text Annotations

Applications

Name
Properties Math Type
Application Specs - Species
Specs - Reaction
Simulations

Application Name: Application

Text Annotations

Annotations will come here

Universal ID's

RFID | pubmed

Specifications (Species) - Application go to Simulations

Species
Initial Condition
Diffusion Constant
RhoGDP 1.0 0.0
RhoGTP 1.0 0.0
GDI 0.7 0.0
GDI_RhoGDP 0.0 0.0
GDI_RhoGTP 0.0 0.0

Specifications (Reaction) - Application go to Simulations

Name
Enabled?
RhoGDP_GDI_binding included
RhoGTP_GDI_binding included

Simulations - Application go to Specifications

Name
End Time
Output Options
Simulation0 600.0 every

Simulation Name: Simulation0

Universal ID's

Text Annotations

Global Parameters

Name
Expression
k3 0.5[min-1]
k2 0.1[min-1]
kcatGEF 5.64[min-1]
KmGEFRho 24.5[umol.l-1]
KmGEFGDI 1.0[umol.l-1]
k1 1.0[l.umol-1.min-1]
kcatGAP 95.9[min-1]
KmGAPGDI 0.1[umol.l-1]
KmGAPRho 4.48[umol.l-1]
k5 0.05[min-1]
k4 0.5[l.umol-1.min-1]
k6 0.5[l.umol-1.min-1]
k7 0.05[min-1]
k8 28.2[l.umol-1.min-1]
k9 0.18[min-1]

Global Parameter Name: k3

Universal ID's

Text Annotations

Global Parameter Name: k2

Universal ID's

Text Annotations

Global Parameter Name: kcatGEF

Universal ID's

Text Annotations

Global Parameter Name: KmGEFRho

Universal ID's

Text Annotations

Global Parameter Name: KmGEFGDI

Universal ID's

Text Annotations

Global Parameter Name: k1

Universal ID's

Text Annotations

Global Parameter Name: kcatGAP

Universal ID's

Text Annotations

Global Parameter Name: KmGAPGDI

Universal ID's

Text Annotations

Global Parameter Name: KmGAPRho

Universal ID's

Text Annotations

Global Parameter Name: k5

Universal ID's

Text Annotations

Global Parameter Name: k4

Universal ID's

Text Annotations

Global Parameter Name: k6

Universal ID's

Text Annotations

Global Parameter Name: k7

Universal ID's

Text Annotations

Global Parameter Name: k8

Universal ID's

Text Annotations

Global Parameter Name: k9

Universal ID's

Text Annotations

Downloads

Format
File
BNGL
Metlab
SBML
Formatted XML
SEDML
Deterministic XML