Physiology

Reaction Diagram

reactionDiagram

Cross-References

Annotations

Reactions

Reactions
Name
Structure
Kinetics
GEF Active_GEF GEF_activation default GeneralKinetics
Active_GEF GEF GEF_inactivation default GeneralKinetics
Activator Activator_degradation default GeneralKinetics

Reaction Name: GEF_activation

Universal ID's

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Reaction Name: GEF_inactivation

Universal ID's

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Reaction Name: Activator_degradation

Universal ID's

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Reaction Name: GEF_activation

Expressions

reaction rate

(Activator * GEF * k1) [umol.l-1.min-1]

Reaction Name: GEF_inactivation

Expressions

reaction rate

(Active_GEF * k2) [umol.l-1.min-1]

Reaction Name: Activator_degradation

Expressions

reaction rate

(Activator * k3) [umol.l-1.min-1]

Structures

Name
Type
Electrical
default Compartment (+)   (-)

Structure Name: default

Universal ID's

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Species

Name
Structure
Activator default
GEF default
Active_GEF default

Species Name: Activator

Universal ID's

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Species Name: GEF

Universal ID's

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Species Name: Active_GEF

Universal ID's

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Molecules

Name
Description
Activator Activator ()
RhoGEF RhoGEF ( Active ~no ~yes )

Molucule Name: Activator

Universal ID's

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Molucule Name: RhoGEF

Universal ID's

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Observables

Name
Domain
Molecular Type
Sequence Type
O0_Activator_tot Molecules Activator Multimolecular
O0_RhoGEF_tot Molecules RhoGEF Multimolecular

Observables Name: O0_Activator_tot

Universal ID's

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Observables Name: O0_RhoGEF_tot

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Applications

Name
Properties Math Type
Canonical Application Specs - Species
Specs - Reaction
Simulations

Application Name: Canonical Application

Text Annotations

Annotations will come here

Universal ID's

RFID | pubmed

Specifications (Species) - Canonical Application go to Simulations

Species
Initial Condition
Diffusion Constant
Activator 1.0 0.0
GEF 0.31 0.0
Active_GEF 0.0 0.0

Specifications (Reaction) - Canonical Application go to Simulations

Name
Enabled?
GEF_activation included
GEF_inactivation included
Activator_degradation included

Simulations - Canonical Application go to Specifications

Name
End Time
Output Options
Simulation0 600.0 every

Simulation Name: Simulation0

Universal ID's

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Global Parameters

Name
Expression
k3 0.5[min-1]
k2 0.1[min-1]
kcatGEF 5.64[min-1]
KmGEFRho 24.5[umol.l-1]
KmGEFGDI 1.0[umol.l-1]
k1 1.0[l.umol-1.min-1]

Global Parameter Name: k3

Universal ID's

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Global Parameter Name: k2

Universal ID's

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Global Parameter Name: kcatGEF

Universal ID's

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Global Parameter Name: KmGEFRho

Universal ID's

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Global Parameter Name: KmGEFGDI

Universal ID's

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Global Parameter Name: k1

Universal ID's

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Downloads

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Deterministic XML