Physiology

Reaction Diagram

reactionDiagram

Cross-References

Annotations

Reactions

Reactions
Name
Structure
Kinetics
Raf1 Raf1_act Raf1_Activation cell GeneralKinetics
Raf1_act Raf1 Raf1_Deactivation cell GeneralKinetics
Raf1_act Raf1 Raf1_Deactivation_Akt cell GeneralKinetics

Structures

Name
Type
Electrical
cell Compartment (+)   (-)

Species

Name
Structure
BioNetGen Definition
Depiction
Ras_act cell Ras(Active~yes!-,).
Raf1_act cell Raf(Active~yes!-,).
Raf1 cell Raf(Active~no!-,).
Akt_act cell Akt(Active~yes!-,).
Raf1PPtase cell Raf(Active~no!-,).P_tase().

Molecules

Name
BioNetGen Definition
DEPICTION
Ras Ras(Active~yes~no,)
Raf Raf(Active~yes~no,)
Akt Akt(Active~yes~no,)
P_tase P_tase()

Observables

Name
Structure
Count
BNGL Definition
Sequence Type
DEPICTION

Applications

Specifications (Species) - Deterministic go to Simulations

Species
Initial Condition
Diffusion Constant
Ras_act 0.0 0.0
Raf1_act 0.0 0.0
Raf1 120000.0 0.0
Akt_act 0.0 0.0
Raf1PPtase 120000.0 0.0

Specifications (Reaction) - Deterministic go to Simulations

Name
Enabled?
Raf1_Activation included
Raf1_Deactivation included
Raf1_Deactivation_Akt included

Simulations - Deterministic go to Specifications

Name
End Time
Output Options

Global Parameters

Name
Expression

Downloads

Format
File
VCML VCML File
BNGL
MatLab
SBML
Formatted XML
SEDML