Physiology

Reaction Diagram

reactionDiagram

Cross-References

Annotations

Reactions

Reactions
Name
Structure
Kinetics
Erk Erk_act Erk_Activation cell GeneralKinetics
Erk_act Erk Erk_Deactivation cell GeneralKinetics

Structures

Name
Type
Electrical
cell Compartment (+)   (-)

Species

Name
Structure
BioNetGen Definition
Depiction
Mek_act cell MEK(Active~yes!-,).
Erk_act cell ERK(Active~yes!-,).
Erk cell ERK(Active~no!-,).
PP2A_act cell PP2A(Active~yes!-,).

Molecules

Name
BioNetGen Definition
DEPICTION
MEK MEK(Active~yes~no,)
ERK ERK(Active~yes~no,)
PP2A PP2A(Active~yes~no,)

Observables

Name
Structure
Count
BNGL Definition
Sequence Type
DEPICTION

Applications

Specifications (Species) - Deterministic go to Simulations

Species
Initial Condition
Diffusion Constant
Mek_act 0.0 0.0
Erk_act 0.0 0.0
Erk 600000.0 0.0
PP2A_act 120000.0 0.0

Specifications (Reaction) - Deterministic go to Simulations

Name
Enabled?
Erk_Activation included
Erk_Deactivation included

Simulations - Deterministic go to Specifications

Name
End Time
Output Options

Global Parameters

Name
Expression
km_inact 3496490.0[mmol.ml-1]
Kcat_inact 8.8912[min-1]
km_act 1007340.0[mmol.ml-1]
Kcat_act 9.85367[min-1]

Downloads

Format
File
VCML VCML File
BNGL
MatLab
SBML
Formatted XML
SEDML