Physiology

Reaction Diagram

reactionDiagram

Cross-References

Annotations

Reactions

Structures

Name
Type
Electrical
compartment Compartment (+)   (-)

Species

Name
Structure
BioNetGen Definition
Depiction
Ca_cell1 compartment Ca().
IP3R_cell1 compartment IP3R_cell1(Ca_bs!-,).

Molecules

Name
BioNetGen Definition
DEPICTION
Ca Ca()
IP3R_cell1 IP3R_cell1(Ca_bs,)

Observables

Name
Structure
Count
BNGL Definition
Sequence Type
DEPICTION
O0_Ca_tot compartment Molecules Ca(). Multimolecular
O0_IP3R_cell1_tot compartment Molecules IP3R_cell1(Ca_bs!?,). Multimolecular

Applications

Specifications (Species) - unnamed go to Simulations

Species
Initial Condition
Diffusion Constant
Ca_cell1 0.3 0.0
IP3R_cell1 0.8 0.0

Specifications (Reaction) - unnamed go to Simulations

Name
Enabled?
IP3R mediated Ca release Cell1 included
ATPase pump mediated Ca release Cell1 included
IP3R independent Ca release Cell1 included
IP3R Inactive to Shut transtition cell1 included
IP3R Open_to_Inactivated_Cell1 included

Simulations - unnamed go to Specifications

Name
End Time
Output Options
Simulation1 30.0 every

Global Parameters

Name
Expression
Phi1_c1 ((r2 * Ca_cell1) / (R1 + Ca_cell1))[tbd]
r2 100.0[tbd]
R1 6.0[tbd]
Phi_minus1_c1 (k1 / (R3 + Ca_cell1))[tbd]
k1 44.0[tbd]
R3 50.0[tbd]
Phi2_c1 ((k2 + (r4 * Ca_cell1)) / (R3 + Ca_cell1))[tbd]
k2 26.5[tbd]
r4 20.0[tbd]
Phi3_c1 (k3 / (R5 + Ca_cell1))[tbd]
k3 1.6[tbd]
R5 1.6[tbd]

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